Endocrine Abstracts

Introduction: Endocrinological and metabolic changes can occur in critically ill patients, which may affect the prognosis and outcome. The hypothalamic–anterior–pituitary axis (HPA) plays a crucial role in the endocrine regulation of metabolic and immunological homeostasis. In this prospective study, we evaluated the pituitary–adrenal–gonadal–thyroid axis in the adult Intensive Care Unit (ICU) patients,their outcome, the association between these hormo...

Introduction: Neoplasms of the thyroid gland are classified according to the cell that it originates and commonly they originate from follicular or parafollicular C cells. The most common differentiated thyroid cancers (DTC) are papillary and follicular carcinomas. Coexistence of two different histological types of primary follicular thyroid neoplasm is a rare condition. There are previous reports of concomitant medullary and papillary thyroid cancers. However, there is scarce...

Introduction: It is unclear whether ultrasonographic (US) findings and fine-needle aspiration biopsy (FNAB) results of nodules accompanied with Hashimoto’s thyroiditis (HT) are affected by the presence of thyroiditis or not. In this study, we compared US features and cytological results of nodules in patients with and without HT.Methods: Patients who underwent FNAB in our clinic were evaluated prospectively. Nodules in patients with and without HT w...

Introduction: Although, vitamin D (vit D) mainly regulates calcium and phosphate metabolisms, its deficiency may also contribute to the development of some carcinomas, autoimmune, and cardiac diseases. Vit D deficiency has been defined to correlate with increased autoimmune disease such as type 1 diabetes mellitus, rheumatoid arthritis, autoimmune thyroid diseases (AITD). Previous studies suggested that patients with AITD had lower vit D levels when compared with healthy contr...

Aim: Exophytic nodule refers to a nodule that sticks out of the normal thyroid boundary/outline. Other definition is a nodule with an acute angle between the lesion and adjacent thyroid capsule. In the literature, one study reported that thyroid nodules with exophytic configuration showed a high malignancy rate. We aimed to compare ultrasonographical features and cytopathologic results of exophytic and non-exophytic thyroid nodules.Material and method: T...

Introduction: Ocular changes and ocular symptoms may be encountered in patients with hypothyroidism and hyperthyroidism. However, the data concerning the effects of thyroid disorders on intraocular pressure (IOP), central corneal thickness (CCT), and retinal thickness (RT) are very rare. Here, we aimed to evaluate the alterations in IOP, CCT, and RT in patients with euthyroid autoimmune thyroiditis (AIT).Methods: Twenty-five subjects with euthyroid AIT w...

Introduction: Diabetes insipidus (DI) is a disease characterized by excessive thirst, polydipsia and excess diluted urine caused by insufficiency of antidiuretic hormone or renal resistance to its effect. Although it is generally a benign condition, severe hypernatremia and hypertonicity may cause death if water loss is not compensated.Case report: A 72-years-old man admitted to our clinic for routine control. In medical history, he told that when he was...

Introduction: Acromegaly is a chronic disease caused by excessive secretion of growth hormone (GH), and as a result, of insulin-like growth factor-1 (IGF1). Although controversial, frequency of both benign and malignant neoplasm formation is thought to be increased in acromegalic patients. Pleomorphic adenoma is the most common arising tumour from the parotid salivary gland. Here we report the case of a 33-year-old woman with acromegaly and also who presented with a swelling o...

Introduction: Xantoma disseminatum (XD) is a rare non-Langerhans cell histiocytosis (NLCH) which is often resistant to treatment. In this report, we presented a case with extensive cutaneous, hypothalamohypophysial, cerebral and gastrointestinal system involvement, which responded well to cyclophosphamide.Case: A 16-year-old female patient admitted to our hospital with the complaints of amenorrhoea, weight gain, polidipsia, poliuria, yellow-brownish papu...

Introduction: Leri–Weill dyschondrosteosis (LWD) is a rare autosomal dominant dyschondrosteosis characterised by Madelung deformity and mesomelic dwarfism. Majority of cases are associated with haploinsufficiency of the short-stature homeobox-containing (SHOX) gene. Here we report a patient with LWD and diabetes mellitus (DM).Case report: A 31 years old man applied with polyuria and polydipsia. He did not have any chronic disease. In family history,...